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This calls for a scale-up of child survival interventions, whose global cost the World Health Organization (WHO) recently estimated for 75 countries that have a high burden of mortality among children aged less than five years.

Each data input category for the costing model (disease incidence, intervention coverage and prices and input volumes for individual-level and programme-level activities) was validated against local data.

Original assumptions were replaced by local data or by recent updated estimates on incidence, coverage and price.

Programme costs are expenses incurred at the district, province or country administrative level (e.g.

in-service training for health workers or information, education and communication activities).

Cost data were provided by countries in their local currencies and were converted to 2004 United States dollars (US$).

When an input price was reported in US$ for a tradable good (such as medicines), we used the US$ deflation rate.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States of America.

In an effort to support the countries in greatest need, WHO’s Department of Child and Adolescent Health and Development (CAH) has identified 33 countries (Appendix A, available at: that together contribute 78% of all deaths among children under 5 years of age.

More details are provided in Appendix C, available at: self-administered questionnaire was developed and sent to WHO experts based in 32 countries with high child mortality in all 6 WHO regions (Appendix A).

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